Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors
This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.
Eligibility
Inclusion Criterea
- Received upfront therapies for osteosarcoma, which included cisplatin, (with or without other agents)
- Patient must have completed cancer treatment >= 2 years prior to study enrollment
- Osteosarcoma survivors without a systemically treated relapse or subsequent malignancy
* Note: History of relapse or second malignancy is permitted if treated with local therapy only (e.g. surgery, radiation)
- Able to speak, read and write in English, French or Spanish
- All patients and/or their parents or legal guardians must sign a written informed consent
- All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met
Participating Clinics
Summerlin Hospital Medical Center
Sunrise Hospital and Medical Center
Renown Regional Medical Center
University Medical Center of Southern Nevada
Alliance for Childhood Diseases/Cure 4 the Kids Foundation