NCI ID NCI-2017-01152
NCT ID NCT03206450
CTEP ID ALTE16C1
Primary Purpose OTHER
Anatomic Sites Bones and Joints
Minimum Age 18 Years
Maximum Age 50 Years
Gender MALE
Lead Org Children's Oncology Group
Principal Investigator Margarett Shnorhavorian
NCI Site View on ClinicalTrials.gov

Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors

This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.

Eligibility

Inclusion Criterea

  • Received upfront therapies for osteosarcoma, which included cisplatin, (with or without other agents)
  • Patient must have completed cancer treatment >= 2 years prior to study enrollment
  • Osteosarcoma survivors without a systemically treated relapse or subsequent malignancy * Note: History of relapse or second malignancy is permitted if treated with local therapy only (e.g. surgery, radiation)
  • Able to speak, read and write in English, French or Spanish
  • All patients and/or their parents or legal guardians must sign a written informed consent
  • All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met

Exclusion Criterea


Participating Clinics

Summerlin Hospital Medical Center


657 Town Center Drive
Las Vegas, NV 89144
Map

702-384-0013
research@sncrf.org

Sunrise Hospital and Medical Center


3186 South Maryland Parkway
Las Vegas, NV 89109
Map

702-384-0013
research@sncrf.org

Renown Regional Medical Center


1155 Mill Street
Reno, NV 89502
Map

702-384-0013
research@sncrf.org

University Medical Center of Southern Nevada


1800 West Charleston Boulevard
Las Vegas, NV 89102
Map

702-384-0013
research@sncrf.org

Alliance for Childhood Diseases/Cure 4 the Kids Foundation


One Breakthrough Way
Las Vegas, NV 89135
Map

702-384-0013
research@sncrf.org